Karl Pfleger received his PhD from Stanford in Computer Science focused on AI & machine learning, especially deepening neural networks. He worked on practical big-data & AI problems in industry: first briefly at mySimon, the then-biggest comparison shopping website, then for a decade at Google before switching to focus entirely on the aging/longevity field.

Karl founded AgingBiotech.info, a free, open, nonprofit resource that serves as the internet's most thorough, organized & structured repository of everything important in the aging field (outside of academia). He is one of the most prolific early-stage investors in the sector, with a focus on rejuvenation biotechs. He is also a dedicated philanthropist for the field with a dozen years of donations to the Buck Institute and other aging-related nonprofits and serves on the board of directors of the Alliance for Longevity Initiatives (A4LI).