Chapter Author
Yu-Xuan
Lyu, PhD.

Dr. Lyu is a rising leader in the field of longevity biotechnology, dedicated to deciphering the biological mechanisms of ageing, with a specific focus on sex-based differences, and developing novel nutraceutical and pharmaceutical interventions and platforms to promote healthy longevity. Currently, he serves as a Research Assistant Professor at Southern University of Science and Technology (SUSTech) and as the Director of the Sirio Institute on Ageing (SIA) in China. He also holds positions as a Researcher at the Faculty of Medicine, Macau University of Science and Technology (MUST), and as a faculty member at the Geneva College of Longevity Science (GCLS). Prior to his current appointments, Dr. Lyu was a Scientist at the Max Planck Institute for Biology of Ageing in Germany. His international contributions earned him the title of "European Future Research Leader" and recognition as a top-tier international talent in Germany. Dr. Lyu has authored multiple high-impact studies in leading journals, including Nature, Nature Aging, Ageing Research Reviews, and eLife. His landmark research, the "Rapamycin for Ageing Trilogy," was honored by the Max Planck Society as an Annual Research Highlight. His findings have been cited in official United Nations reports and featured in Nature research highlights. Furthermore, his work has garnered significant media attention from prominent international and domestic outlets, including Germany’s ARD television network, EurekAlert!, and DeepTech, etc. Beyond his academic pursuits, Dr. Lyu is deeply committed to the industrial application of longevity science. He actively works to translate laboratory innovations into commercial development, driving the creation of new ageing intervention discovery platforms. His current research focuses on critical areas such as metabolic health, immune homeostasis, and the development of natural products as viable ageing interventions. Expanding his impact into the "One Health" domain, Dr. Lyu initiated a pioneering domestic dog ageing project in China, which aims to promote the health and longevity of both humans and their beloved pets.